MGH/BWH Combined ID Fellowship
Clinical Training
Training in the Second Year and Beyond
Application Process
MGH/BWH Combined ID Fellowship
The Massachusetts General and Brigham and Women's
Hospitals have integrated their Infectious Disease
Fellowship Training Programs to offer unparalleled
opportunities for clinical and research training
in Infectious Diseases at Harvard Medical School.
The central mission of the program is trainee
career development. The joint faculties are committed
to providing each trainee with the educational
opportunities, mentoring support, and resources
necessary for the trainee's objectives in infectious
disease clinical care, teaching, and research
in clinical and laboratory settings. We view the
training of future teachers and investigators
as our most enduring contribution to medical science.
We are eager to assist in the training of women
and minority candidates.
Fellows usually come for between two and four
years of training, depending on background
and career interest. Occasionally, fellows come
for one year of training as part of a training
plan involving other institutions. Most fellows
spend the first year in clinical training and
subsequent years in further preparation for a
career as a clinician teacher, as a clinical
investigator, or as a laboratory investigator
(see below).
Clinical Training
Each fellow has a "home base" either
at the Brigham and Women's Hospital (BWH) or
at the Massachusetts General Hospital (MGH).
During the clinical training year, fellows spend
slightly more time at the home institution than
at the other institution, but all fellows participate
in all available rotations at both hospitals
over the course of the year. Extensive and intensive
interactions between each fellow and the faculty
of both institutions are the cornerstone of the
program. Fellows arrange their program so that
it meets the requirements of the Subspecialty
Certifying Examination in Infectious Diseases
of the American Board of Internal Medicine. Foreign
Certification Board requirements can also be
met frequently.
The MGH and BWH are acute care general hospitals
with large outpatient clinics, affiliated primary
care providers, and active emergency rooms.
The MGH and BWH have 898 and 730 beds, respectively,
devoted to primary, secondary, and tertiary
inpatient care. Inpatients include those on
general medical, medical subspecialty, general
surgical, surgical subspecialty, neurological/neurosurgical,
obstetrical or gynecological, and pediatric
services. The BWH and MGH have several intensive
care units, bone marrow and organ transplantation,
oncology, and AIDS treatment populations. The
clinical activities of the Dana Farber Cancer
Institute are now fully integrated with the
BWH and the MGH. The MGH has a Pediatric Service
and a large Burn Unit, and ophthalmology and
otolaryngology services are provided at the
nearby Massachusetts Eye and Ear Infirmary (MEEI).
Both MGH and BWH have a full range of outstanding
medical, surgical, neurological, obstetrical,
gynecological, pathological, and radiological
expertise. Infectious Disease consultations
are important in the operations of all services
at these hospitals. Rotations also occur at
the affiliated Boston Children's Hospital.
A typical clinical training year includes inpatient
consultations, outpatient consultations and
primary care of patients with HIV infection,
a rotation in the Clinical Microbiology Laboratory,
a rotation in Pediatric Infectious Diseases, an ambulatory block rotation focused
on sexually transmitted diseases (STDs), travel
medicine, tropical medicine, mycobacterial diseases,
and Teaching Conferences. Specific experience
is provided in Transplantation Infectious Disease,
care of patients with HIV infection and malignancies,
and hospital Infection Control and epidemiology.
Inpatient consultations are rendered daily by
a consult team consisting of an Attending Physician,
one or two fellows, and frequently medical residents
and medical students. Generally one to three
new patients are seen by each fellow each day.
Each patient's problems are an opportunity for
exemplary consultative care and for the dissemination
of information among the members of the consult
team and to other services. Fellows have a continuity
Outpatient Clinic with the same Attending Physician
one half-day session per week at their home-base
hospital for two years.
Clinical conferences are important learning
and teaching experiences. Weekly lectures at
the beginning of the year provide a core of
Infectious Disease knowledge and approaches.
Weekly management conferences at each institution
are an opportunity to gain the views of the entire
faculty about the previous week's cases. A joint
weekly conference brings the entire group of
Infectious Disease faculties from BWH, MGH,
DFCI, and the other Harvard-affiliated hospitals
together for case-oriented, in-depth discussions
and for research presentations by senior fellows
or faculty. A weekly conference on HIV includes
management, relevant research, and a journal
club. MGH and BWH also have Medical Grand Rounds
and Morbidity and Mortality Conferences, which
are core activities of the Medical Services.
Training in the Second Year
and Beyond
After the year of clinical training, fellows
pursue additional training to meet Board
requirements in Infectious Diseases, as well
as to prepare for their desired career paths.
The majority of the fellows training in the
combined Massachusetts General Hospital and
Brigham Women’s
Hospital ID Fellowship pursue additional
investigative training in areas ranging from
basic science through translational investigation
to clinical research and epidemiology. Fellows
select a mentor from the Infectious Disease
faculty at either the MGH or BWH.
for an in-depth research experience. Some fellows
pursue basic research training with other faculty
at Harvard Medical School, in the Microbiology
and Molecular Genetics Department, in Immunology,
in Virology, or in Parasitology. Many of the
faculty of the MGH and BWH Infectious Disease
Divisions have joint appointments in these Departments
and Programs and are also part of these training
communities. Depending
on past background and experience, this investigative
training path generally takes 2-4 years of additional
training under the mentorship of an individual
faculty member, as described below. Other
fellows pursue training as clinician-educators
in the fields of HIV medicine or in transplantation
Infectious Diseases, sometimes combined with
additional investigative training as described
below. Key to the success of each of these
training paths is the establishment of a
personal relationship with an individual
mentor to help guide the fellow through his/her
training years.
- Investigative Training in Infectious Diseases
Fellows wishing to prepare for a career
as an independently funded investigator pursue
additional training under the guidance of
an individual faculty mentor, in fields such
as basic laboratory science, translational
investigation, clinical research, epidemiology,
or other areas. The key to the success of
such a training path depends on identification
of a faculty mentor to help guide the fellow
during the training period. Potential individual
mentors have research funding of their own
to support training of post-doctoral fellows,
and also serve as mentors on institutional
training grants that can support such training.
After sufficient experience and expertise
has been developed, post-doctoral fellows
are encouraged to compete for one of the
Career Development Award programs funded
through the National Institutes of Health,
including the K08 Award (Mentored Clinical
Scientist Career Development Award), the
K23 Award (Mentored Patient-Oriented Research
Career Development Award), and K01 (Mentored
Research Scientist Development Award), or
the International Research Scientist Development
Award from the Fogarty International Center.
These awards allow a more extended period
of investigative training and the transition
from post-doctoral fellow to faculty status
as increasing independence from the mentor
develops.
Several of the most commonly used training
grants available to Infectious Disease fellows
and mentors serving on these training grants,
are listed below.
- Infectious Disease and Basic Microbiological
Mechanisms Training Grant
T32 AI 007061
Dennis L. Kasper, PI
Description
The Harvard Medical School-based
research training program entitled “Infectious
Diseases and Basic Microbiological Mechanisms” offers
laboratory-based research training for physicians
and postdoctoral PhD scientists. The aim
is to provide substantive research training
experience with relevant supporting course
work and thereby to enable the postdoctoral
trainee to become an independent investigator
in the fields of infectious diseases and
microbiology. Training laboratories are available
in eight major areas (1) virology, (2) bacteriology,
(3) parasitology, (4) immunology, (5) molecular
biology and genetics, (6) cell biology, (7)
epidemiology, and (8) biochemistry.
List of Current Mentors
Beth Israel Deaconess Medical Center:
Clyde S. Crumpacker, M.D., Professor of Medicine
Joyce D. Fingeroth, M.D., Associate Professor
of Medicine
Margaret Koziel, M.D., Associate Professor
of Medicine
Norman Letvin, M.D., Professor of Medicine
Anne Nicholson-Weller, M.D., Professor of
Medicine
Priscilla A. Schaffer, Ph.D., Professor
of Medicine (Microbiology & Molecular
Genetics)
Peter F. Weller, M.D., Professor of Medicine
Brigham and Women’s Hospital and Channing
Laboratory:
Laurie Comstock, Ph.D., Assistant Professor
of Medicine
Dennis L. Kasper, M.D., Professor of
Medicine & Professor
of Microbiology & Molecular Genetics
Elliott Kieff, M.D., Ph. D., Professor
of Medicine & Professor of Microbiology & Molecular
Genetics
Jean C. Lee, M.D., Associate Professor of
Medicine
Lawrence C. Madoff, M.D., Assistant Professor
of Medicine
D. Branch Moody, M.D., Associate Professor
of Medicine
Andrew B. Onderdonk, Ph.D., Professor of
Pathology
Lawrence C. Paoletti, Ph.D., Assistant Professor
of Medicine
Gerald B. Pier, Ph.D., Professor of Medicine
(Microbiology & Molecular Genetics)
Richard Platt, M.D., Professor of Ambulatory
Care and Prevention
Arthur Tzianabos, Ph.D., Associate Professor
of Medicine
Frederick C.S. Wang, M.D., Professor
of Medicine
Children’s Hospital Medical
Center:
Anna Aldovini, M.D., Assistant Professor
of Pediatrics
Simon L. Dove, Ph.D., Assistant Professor
of Pediatrics
Donald A. Goldmann, M.D., Professor of
Pediatrics
Robert Husson, M.D., Assistant Professor
of Pediatrics
Kenneth McIntosh, M.D., Professor of Pediatrics
Paula I. Watnick, M.D., Ph.D., Assistant
Professor of Pediatrics
Michael R. Wessels, M.D., Professor
of Pediatrics (Microbiology & Molecular
Genetics)
Harvard Medical School:
Department of Microbiology and Molecular
Genetics
Jonathan R. Beckwith, Ph.D., Professor
of Microbiology and Molecular Genetics
R. John Collier, Ph.D., Professor of Microbiology
and Molecular Genetics
Darren Higgins, Ph.D., Assistant Professor
of Microbiology and Molecular Genetics
David M. Knipe, Ph.D., Professor of Microbiology
and Molecular Genetics
Roberto G. Kolter, Ph.D., Professor of
Microbiology and Molecular Genetics
Stephen Lory, Ph.D., Professor of Microbiology
and Molecular Genetics
John J. Mekalanos, Ph.D., Professor of
Microbiology and Molecular Genetics
Max L. Nibert, M.D., Ph.D., Associate Professor
of Microbiology and Molecular Genetics
David Z. Rudner, Ph.D., Assistant Professor
of Microbiology and Molecular Genetics
Michael N. Starnbach, Ph.D., Associate
Professor of Microbiology and Molecular
Genetics
Sean P.J. Whelan, Ph.D., Assistant Professor
of Microbiology and Molecular Genetics
Suzanne Walker, Ph.D., Professor of Microbiology
and Molecular Genetics
Harvard School of Public Health:
Eric Rubin, M.D., Ph.D., Assistant Professor
of Immunology and Infectious Diseases
Dyann F. Wirth, Ph.D., Professor of Tropical
Public Health
Massachusetts General Hospital:
Stephen B. Calderwood, M.D., Professor
of Medicine (Microbiology & Molecular
Genetics)
Marcia B. Goldberg, M.D., Associate
Professor of Medicine (Microbiology & Molecular
Genetics)
Elizabeth L. Hohmann, M.D., Associate Professor
of Medicine
David C. Hooper, M.D., Professor
of Medicine
Cammie Lesser, M.D., Ph.D., Assistant
Professor of Medicine (Microbiology & Molecular
Genetics)
Andrew D. Luster, M.D., Ph.D., Professor
of Medicine
Megan Murray, M.D., Assistant Professor
of Epidemiology
Mark Poznansky, M. D., Ph.D., Assistant
Professor of Medicine
Edward T. Ryan, M.D., Associate Professor
of Medicine
Bruce D. Walker, M.D., Professor of Medicine
H. Shaw Warren, M.D., Associate Professor
of Pediatrics
- Multidisciplinary AIDS Training Grant
T32 AI07387
Martin S. Hirsch, PI
Description:
The primary purpose of this training program
is the development of scientific leaders
for careers in HIV/AIDS research. The current
expanding epidemic of HIV infection demands
commitment of investigators to the training
of a new generation of leaders in research.
It is anticipated that graduates of this
postdoctoral program will follow careers
in laboratory research related to AIDS. This
program will provide in depth laboratory
experience in a specific research area of
virology, immunology, molecular biology,
oncology, molecular genetics, or molecular
therapeutics to selected candidates. Trainees
will be MDs after completion of their clinical
residencies and specialty training or PhDs
and ScDs from an appropriate basic science
program. Criteria for selection will include
prior training record, aptitude for research,
and commitment to research careers.
The basic elements of the program are:
1) in depth research training through laboratory
investigation of a specific problem in
a particular area related to HIV/AIDS under
a senior investigator; 2) a didactic program
consisting of appropriately chosen specific
courses that will advance the trainee’s
knowledge; 3) frequent exposure to seminars,
workshops, and colloquia related to HIV/AIDS;
4) regular review of progress by individual
Progress Evaluation Committees and the
Program Steering Committee.
The primary training facilities consist
of well-equipped research laboratories
at Harvard Medical School, Harvard School
of Public Health, Massachusetts General
Hospital, Beth Israel-Deaconess Medical
Center, Brigham and Women’s Hospital,
Boston Children’s Hospital, Dana-Farber
Cancer Institute, and the New England Regional
Primate Research Center. Senior faculty
members at each of these institutions are
mentors on this grant, and they represent
a variety of disciplines. The faculty members
collaborate with one another on HIV/AIDS
research and will collaborate in directing
this training program.
List of Current Mentors
Beth Israel Deaconess Medical Center:
Daniel Barouch, M.D., Ph.D., Assistant Professor of Medicine
Clyde Crumpacker, M.D., Professor of Medicine
Igor J. Koralnik, M.D., Associate Professor of Neurology
Norman Letvin, M.D., Professor of Medicine
Brigham and Women’s Hospital:
Elliott Kieff, M.D., Ph.D., Professor of Medicine, and Professor of Microbiology and Molecular
Genetics
Daniel Kuritzkes, M.D., Professor of Medicine
Children’s Hospital Medical
Center:
Marian Neutra, Ph.D., Professor of Pediatrics
Dana-Farber Cancer Institute:
Dana Gabuzda, M.D., Professor of Neurology
Harvard Institute of Medicine:
Ernest Terwilliger, M.D., Assistant Professor
of Medicine
Harvard School of Public Health:
Max Essex, DVM, Ph.D., Professor of Immunology
and Infectious Diseases
Phyllis Kanki, DVM, DSc., Professor of
Immunology and Infectious Diseases
Tun-Hou Lee, DSc., Professor of Immunology
and Infectious Diseases
Massachusetts General Hospital:
Marcus Altfeld, M.D., Ph.D., Assistant
Professor of Medicine
Steven Grinspoon, M.D., Associate Professor
of Medicine
Andrew Luster, M.D., Ph.D., Professor of
Medicine
Mark Poznansky, M.D., Ph.D., Assistant
Professor of Medicine
Eric Rosenberg, M.D., Assistant Professor
of Medicine
David Scadden, M.D., Professor of Medicine
Bruce Walker, M.D., Professor of Medicine
New England Regional Primate Research
Center:
Ronald Desrosiers, Ph.D., Professor of
Microbiology and Molecular Genetics
Michael J. Farzan, Ph.D., Assistant Professor
of Microbiology and Molecular
Genetics
R. Paul Johnson, M.D., Associate Professor
of Medicine
-
Program for AIDS Clinical
Research Training (PACRT)
T32 AI007433
Kenneth A. Freedberg, PI
Description
The goal of the Program for AIDS Clinical
Research Training (PACRT) is to provide
broad training in quantitative research
methodologies and closely supervised research
experience to both infectious disease and
other physicians at an early stage in their
careers, as well as to pre-doctoral PhD
students with a focus on HIV clinical research.
This training will prepare both groups
to conduct clinical research of direct
relevance to the prevention and treatment
of HIV infection, and it will prepare them
for the next phase of development as independent
investigators using the mechanism of the
K01, K08, K23, and K25 awards. This training
program has the following three specific
aims:
1) Acquisition of a sufficient body of
knowledge of quantitative methods to permit
trainees to conduct independent research
in one or more of the following areas:
clinical epidemiology, biostatistics, clinical
trials, decision sciences and outcomes
research, and clinical virology or clinical
immunology. This aim will be accomplished
through pursuit of a core of didactic coursework
at the Harvard School of Public Health.
2) Development of a primary area of research
expertise and focus for the trainee. This
aim will be accomplished by a minimum of
two years of direct research experience
under the close supervision of one or more
PACRT faculty mentors. Progress will be
monitored by both the faculty mentor and
the PACRT Steering Committee.
3) Acquisition of broad understanding
of the various aspects of HIV infection
in order to permit the trainee to engage
in novel interdisciplinary research.
This aim will be accomplished through
attendance at regular seminars and meetings
of direct relevance to HIV research.
These meetings include: a weekly HIV Clinical
Conference at Massachusetts General Hospital;
a weekly journal club in the Infectious
Disease Division at the Brigham & Women’s
Hospital; a weekly journal club in the
Infectious Disease Division at the Beth
Israel Deaconess Medical Center; a three
times monthly HIV Clinical Research-In-Progress
meeting based at the Massachusetts General
and Brigham & Women’s Hospitals,
and monthly HIV research meetings at
the Harvard School of Public Health.
Trainees in past years represented the
breadth of institutions that make up this
training grant, including the Beth Israel
Deaconess Medical Center, the Massachusetts
General Hospital, Brigham and Women’s
Hospital, and the Harvard School of Public
Health. They have carried out research
on HIV disease both in the US and internationally.
All trainees have had opportunities to
present their work to fellow trainees,
as well as to more senior faculty at one
or more of the conferences described above.
List of Current Mentors
Massachusetts General Hospital:
Kenneth A. Freedberg, M.D., MSc, Associate
Professor of Medicine
Raymond T. Chung, M.D., Assistant Professor
of Medicine
Martin S. Hirsch, M.D., Professor of Medicine
Valerie E. Stone, M.D., M.P.H., Associate
Professor of Medicine
Bruce D. Walker, M.D., Professor of Medicine
Eric S. Rosenberg, M.D., Assistant Professor
of Medicine
Harvard Medical School:
Jim Y. Kim, M.D., Ph.D., Director, Program
in Infectious Disease and Social Change
Paul D. Cleary, Ph.D., Professor of Health
Care Policy
Erica D’Agata, M.D., M.P.H., Assistant
Professor of Medicine
Harvard School of Public Health:
Megan Murray, M.D., Sc.D., Assistant Professor
of Epidemiology
Robert J. Blendon, Sc.D., Professor of
Health Policy and Management
Sue J. Goldie, M.D., M.P.H., Professor
of Health Decision Science
Marc Lipsitch, D Phil, Associate Professor
of Epidemiology
George R. Seage, III, Sc.D., M.P.H., Associate
Professor of Epidemiology
Milton C. Weinstein, Ph.D., Professor of
Health Policy and Management
Beth Israel Deaconess Medical Center:
A.W. Karchmer, M.D., Professor of Medicine
Margaret Koziel, M.D., Associate Professor
of Medicine
Brigham and Women’s Hospital:
Paul E. Sax, M.D., Associate Professor
of Medicine
Joia S. Mukherjee, M.D., M.P.H., Medical
Director, Partners In Health
Paul Farmer, M.D., Ph.D., Professor of
Medical Anthropology
- Other
Training Grants on Which ID Division Faculty
Serve as Mentors
A. Training Grant in Transplantation
Biology
T32 AI07529
David H. Sachs, M.D., PI
Description
This program supports pre- and post-doctoral
trainees with the major
goal of producing outstanding independent
investigators capable of addressing fundamental
questions in the fields of immunology
and transplantation. This program offers
a minimum of 2 years of laboratory-based
research training for physicians and
postdoctoral Ph.D. scientists. The program
integrates substantive research training
with relevant supporting course work
and research seminars. Training is focused
on the basic science program of the Transplantation
Biology Research Center, including investigation
of allotransplantation and xenotransplantation
in hematopoietic stem cell and
organ transplantation. There are particular
interests in preclinical models of tolerance
induction for clinical application. The
postdoctoral trainee will benefit from
interdisciplinary training in molecular
virology, immunology, pathology, and
transplantation. For Infectious Disease
trainees, research in the laboratory
of Dr. Jay Fishman is focused on the
pathogenesis of infections in immunosuppressed
hosts with an emphasis on molecular
virology and xenotransplantation. The
components of this program include:
1) research training through laboratory
investigation of a specific problem related
to immunology and transplantation infectious
disease; 2) appropriately chosen courses
which will advance the trainee’s
knowledge; 3) frequent
exposure to seminars, workshops, and
colloquia related to immunology and infectious
diseases; 4) regular review of the progress
by the individual mentors and the Program
Steering Committee.
Massachusetts General Hospital:
Mentor: Jay A. Fishman, M.D., Associate
Professor of Medicine
- Training as Clinician-Scholars in
HIV Medicine or Transplantation ID
Some fellows pursue training as clinician-educators
in the fields of HIV medicine
or in transplantation Infectious Diseases,
sometimes combined with additional investigative
training as described above.
- HIV Clinician-Educator
Tracks (One spot at the BWH
and one at the MGH each year)
The primary
purpose of this track is to train outstanding
clinical educators in the field of HIV medicine.
The ideal candidate for this position is
a fellow who wishes to focus on HIV clinical
care and education beyond what is learned
through the standard infectious diseases
fellowship. This path may also be well-suited
for a fellow interested in a career in global
HIV who desires additional
focused training in the clinical care of
HIV-infected patients. Fellows spend one
year in this track, generally during the
second year of their infectious diseases
training. Each year in this track there is
one position at the BWH and one at the MGH.
The main components of the HIV Clinician
Educator Track are 1) outpatient
and inpatient clinical work with
an emphasis on longitudinal HIV care;
2) developing expertise in the use
of antiretroviral therapy, management
of HIV-related complications, interpretation
of resistance testing, and use of
experimental agents; 3) organizing
the respective hospital’s
(MGH or BWH) weekly HIV clinical
conference; 4) providing consultation
for occupational and non-occupational
administration of post-exposure HIV
prophylaxis; 5) educating other fellows,
residents, and medical students on
HIV-related topics; 6) recruitment
of subjects for on-site HIV clinical
trials. A key additional component
of the HIV Clinician-Educator track
is for the fellow to take the lead
on an academic project that will
lead to a conference abstract, a
review paper, or a book chapter.
This project will be done under the
mentorship of one of the Senior Faculty
at his or her respective institution.
After completion of the second-year HIV
Clinician-Educator track, fellows are eligible
to take the certication examination of teh ABIM in the subspecialty of Infectious Disease and may seek a staff position in the clinical
educator role. Alternatively, several fellows
have used this HIV Clinical year as a springboard
to other research projects and training
related to HIV clinical and translational
research, both here and internationally.
If this path is chosen, fellows will be
expected to identify during their second
year an appropriate research mentor to
help them apply for funding in this area.
Supervising faculty:
BWH:
Paul Sax, M.D., Clinical Director,
Brigham and Women’s Division
of Infectious
Diseases and HIV Program
Dan Kuritzkes, M.D., Director
of AIDS Research, Brigham
and Women’s
Hospital
Sigal Yawetz, M.D., Associate Physician, Brigham and Women's Hospital
Todd Ellerin, M.D.,
MGH:
Raj Gandhi, M.D., Director, HIV Clinical
Services and HIV Education, MGH
Nesli Basgoz, M.D., Associate Chief and
Clinical Director, Infectious Diseases,
MGH
Ben Davis, M.D., Associate Physician, MGH
Kimon Zachary, M.D., Associate Physician, MGH
More details regarding the HIV Clinician-Educator
Track may be found at
http://www.massgeneral.org/id/education_and_training/fellowship_training/goals/
- Transplantation ID Tracks
MGH Fellowship Program in Clinical
Care and Investigation in the Immunocompromised
Host
Jay A. Fishman M.D., Director,
MGH Transplant Infectious Disease
and Compromised Host Program
This program provides advanced
training in the clinical
care of immunocompromised patients
and clinical investigation in Transplantation
Infectious Diseases.
Infectious Disease Fellows will enter
this program after completion of
one clinical year in Infectious Diseases.
The MGH Transplantation
Infectious Disease and Compromised
Host Program was established to facilitate
the evaluation, prevention, and treatment
of infectious diseases
in liver, heart, lung, kidney, pancreas
and Hematopoitic stem cell translpant recipients at the Massachusetts
General Hospital.
These patients are unique in the
complexity of their immune deficits,
in their predisposition to opportunistic
infection, and in
the need to understand the management
of antimicrobial therapies and of
drug interactions for optimal clinical
care. The goal of the program is
an individualized approach to acquiring
knowledge about immunosuppressive
therapies (exogenous immune suppression),
immune defects (innate
or acquired), modern diagnostics,
and antimicrobial therapies (prophylaxis
and treatment). The trainee also
benefits from ongoing interactions
with expert clinicians in Transplant
Surgery and Hematology-Oncology and
basic research scientists studying
preclinical models of transplantation
in the Infectious Disease Division,
Transplant Unit and Transplantation
Biology Research Center.
The optimization of care requires
experience in the management of
these complex patients and an understanding
of the relationships between immune
deficiency and the prevention of
infection. Each Fellow will spend
1-2 years in a combination of clinical
training and clinical investigation.
Individualized programs will
be developed to include:
1) mentored experience caring for
immunocompromised patients; 2) clinical
and translational research training
through participation in studies
of a specific problem in clinical
immunology and transplantation infectious
disease; 3) appropriately chosen
courses that will advance the trainee’s knowledge;
4) frequent exposure to seminars,
workshops, and colloquia related
to immunology and infectious diseases;
4) regular review of the trainee’s
progress. The expectation
is that candidates
will become superior
clinicians and will
develop peer-reviewed
publications as a part
of their training program.
Criteria for selection
include prior training
record, clinical expertise,
aptitude for research,
and commitment to the
care of immunocompromised
hosts.
BWH/DFCI Transplant/Oncologic
Infectious Diseases Training Pathway
Mentors and supervising faculty:
Lindsey R. Baden, M. D., Director, Dana-Farber Cancer Institute Division of Infectious Disease
Francisco M. Marty, M. D., Associate Physician, Brigham and Women's Hospital
Robert H. Rubin, M. D., Associate Director, Brigham and Women's Hospital, Division of Infectious Diseases,
Brigham & Women's Hospital
and Dana-Farber Cancer
Institute provide a rich and
environment for advanced
Infectious Diseases training in the
areas of oncologic and transplant
infectious diseases. The ID Division
provides consultation services for
a high volume of patients with complex
infectious disease
issues resulting from transplantation
(both hematopoietic stem cell and
solid organ, with several hundred
transplants performed each year)
and oncologic care. Services are
provided in both the inpatient and
outpatient setting.
We are engaged in diverse aspects
of clinical research in this patient
population:
a. Defining and refining the clinical
epidemiology of opportunistic and
non-opportunistic infections in
diverse cohorts (leukemia,
HSCT and lung transplantation).
b. Development and validation of
new diagnostic tests and strategies
to optimize the care of the immunocompromised
host.
c. Design and conduct of local
and multicenter clinical trials
of new antivirals, antibacterials,
and antifungals.
d. Collaborative research with
basic scientists to understand
different aspects of the immunology,
pathology and pathophysiology of
opportunistic infections in this
population.
There are opportunities for advanced
training in clinical
care and clinical research for interested
ID fellows. Such
training will be tailored to the
fellow’s
specific interests
Application Process
January 15, 2008 was the deadline for receipt
of applications for positions in the Clinical
Fellowship program beginning in July 2009.
Applications to the ACGME Fellowship beginning
in July 2009 will be accepted via ERAS (Electronic Residency Application Service)
from July 1, 2007 - January 15, 2008.
We also have Research Training opportunities
outside the ACGME-Certified Program. Applicants
wishing to have additional research training
may contact individual faculty members about
potential positions in their basic or clinical
research programs. If you wish information about
our faculty and their research interests, you
should contact the fellowship coordinator, Shannon
Rogers-Cruz . |
